Broad Area: Bioengineering and Biomedical sciences

Specialization: Biomolecular Nano-Imaging and Interaction, Biomaterials, Tissue Engineering, Hemorheology

Research Interests: 3-D Structure and Dynamics of Biomolecules at Solid-Liquid Interface, Biosensors, Surface Modifications and Nanofabrication of Materials to improve Biosensing, Biocompatibility and Scaffolding for Tissue Engineering

CURRENT ACADEMIC AND RESEARCH ACTIVITIES

I. ResearcherID: K-3524-2012
      URL: http://www.researcherid.com/rid/K-3524-2012

II. Research Supports (Funded Strategic Projects from KACST)

• Project Number: 11-NAN1544-03 

Title: Synthesis and characterization of conductive nanocomposites (enhanced material) for nanoengineered bone tissue engineering
Role: PI

• Project Number: 8-NAN132-3

Title: Fabrication and characterization of GaN-based nano-structure devices
Role: Co-PI

III. Recent Publications

• Journals

1. D. Banerjee, R. Adari, S. Sankaranarayan, A. Kumar, S. Ganguly, R. W. Aldhaheri, M. A. Hussain, A. S. Balamesh, and D. Saha (2013). Electrical Spin Injection using GaCrN in a GaN based Spin Light Emitting Diode, Applied Physics Letters, (Accepted, L13-08943R2).
2. P. Khalid, M. A. Hussain, P. D. Rekha, and A. B. Arun (2013). Synthesis and characterisation of Carbon Nanotubes Reinforced Hydroxyapatite composite, INDJST, (In Press)
3. P. Khalid, M. A. Hussain, P. D. Rekha, V. B. Suman, and A. B. Arun (2013). Modifications of Carbon Nanotubes for Bio-applications and Toxicity Evaluations, J. Environ. Nanotechnol., Vol. 2 (1), 70-74.
4. T. Patil, N. Pande, R. Adari, P. Suggisetti, N. Raorane, S. Ganguly, R. W. Aldhaheri, M. A. Hussain, and D. Saha (2012)."Cl₂/Ar Based Dry Etching of GaCrN using Inductively Coupled Plasma", Journal of Nanoelectronics and Optoelectornics, Vol. 7, 1-4.
5. A. Kamath, T. Patil, R. Adari, I. Bhattacharya, S. Ganguly, R.W. Aldhaheri, M.A. Hussain, and D. Saha (2012). Double Channel AlGaN/GaN High Electron Mobility Transistor with Back Barriers. IEEE Electron Device Letters, Vol. 33, No. 12, 1690-1692.

http://ieeexplore.ieee.org/stamp/stamp.jsp?tp=&arnumber=6332471

6. M. Anaul Kabir,  Mohammad Asif Hussain and Zulfiqar Ahmad (2012). Candida albican: A model organism for studying fungal pathogens, ISRN Microbiology, Vol.2012, 1-15.
7. Smita Amarnath,  Mohammad A. Hussain,  Vidyanand Nanjundiah  and A. K. Sood (2012). b-galactosidase Leakage From Escherichia coli Points to Mechanical Damage as Likely Cause of Carbon Nanotube Toxicity. Soft Nanoscience Letters, Vol.2, (3), 41-45.

• Presentation in International ISI listed and other Conferences

1. Abdelmoamen K. Aljehani, Mohammed A. Hussaini, Mohammad A. Hussain, Nazeeh Sh Alothmany, and Rabah W. Aldhaheri (2014). Effect of Electrospinning Parameters on Nanofiber Diameter Made of Poly (vinyl alcohol) as Determined by Atomic Force Microscopy. Accepted for presentation in 2nd Middle East Conference on Biomedical Engineering, to be held Hilton Hotel, Doha, Qatar, (IEEE listed conference) February 17-20, 2014. 
   
2. Rama Adari, Debashree Banerjeey, Swaroop Ganguly, Rabah W. Aldhaheri, Mohammad A. Hussain, and Dipankar Saha. Characteristics of Ferromagnetic Schottky Diodes on Heavily n-Doped GaN Semiconductor, to be presented in The 8th EDSSC, sponsored by Electrical Engineering Department, Chulalongkorn University, Bangkok, IEEE Thailand Section, IEEE Electron Device Society, and IEEE ED/SSC Hong Kong Joint Chapter, Bangkok, Thailand during December 3-5, 2012. 
3. Paper presented in ISI listed conference AMEE (2012). Submission ID is IWNO-47 and titled is "Cl₂/Ar Based Dry Etching of GaCrN using Inductively Coupled Plasma" (ISI listed conference) http://iwno.iwamee.com/JNO.html
4. Bahattin Karagözoglu, Nazeeh S. Al-Othmany, M. A. Hussain, and Abdelhameed F. Al-Khateeb (2011). A Proposal for Master of Science (M.Sc.) Program in Biomedical Engineering (BME) at King Abdulaziz University. In: Proceeding of the first Middle East Conference on Biomedical Engineering (MECBME’11), Sharjah, UAE, Feb. 22-25, 2011

FULL LIST OF PUBLICATIONS

1. D. Banerjee, R. Adari, S. Sankaranarayan, A. Kumar, S. Ganguly, R. W. Aldhaheri, M. A. Hussain, A. S. Balamesh, and D. Saha (2013). Electrical Spin Injection using GaCrN in a GaN based Spin Light Emitting Diode, Applied Physics Letters, (Accepted, L13-08943R2).
2. P. Khalid, M. A. Hussain, P. D. Rekha, and A. B. Arun (2013). Synthesis and characterisation of Carbon Nanotubes Reinforced Hydroxyapatite composite, INDJST, (In Press)
3. P. Khalid, M. A. Hussain, P. D. Rekha, V. B. Suman, and A. B. Arun (2013). Modifications of Carbon Nanotubes for Bio-applications and Toxicity Evaluations, J. Environ. Nanotechnol., Vol. 2 (1), 70-74.
4. T. Patil, N. Pande, R. Adari, P. Suggisetti, N. Raorane, S. Ganguly, R. W. Aldhaheri, M. A. Hussain, and D. Saha (2012)."Cl₂/Ar Based Dry Etching of GaCrN using Inductively Coupled Plasma", Journal of Nanoelectronics and Optoelectornics, Vol. 7, 1-4.
5. A. Kamath, T. Patil, R. Adari, I. Bhattacharya, S. Ganguly, R.W. Aldhaheri, M.A. Hussain, and D. Saha (2012). Double Channel AlGaN/GaN High Electron Mobility Transistor with Back Barriers. IEEE Electron Device Letters, Vol. 33, No. 12, 1690-1692.

http://ieeexplore.ieee.org/stamp/stamp.jsp?tp=&arnumber=6332471

6. M. Anaul Kabir,  Mohammad Asif Hussain and Zulfiqar Ahmad (2012). Candida albican: A model organism for studying fungal pathogens, ISRN Microbiology, Vol.2012, 1-15.
7. Smita Amarnath,  Mohammad A. Hussain,  Vidyanand Nanjundiah  and A. K. Sood (2012). b-galactosidase Leakage From Escherichia coli Points to Mechanical Damage as Likely Cause of Carbon Nanotube Toxicity. Soft Nanoscience Letters, Vol.2, (3), 41-45.
8. Perwez K., Perwez S., Kumar N.A. and Hussain M.A. (2011): Leptospirosis in Febrile Patients: Diagnosis by Serology and Polymerase Chain Reaction. Journal of Biology and Life Science. 2(1): E3
9. Hussain M.A., Kabir M.A. and Sood A.K. (2009): On the Cytotoxicity of Carbon Nanotubes. Current Science. 96: 664-673.
10. Kabir M.A. and Hussain M.A. (2009): Human fungal pathogen Candida albicans in the post genomic era: An overview. Expert Rev. Anti Infect. Ther. 7: 121-134.
11. Naama L., Hussain M.A. and Mao J.J. (2008): Investigation of Nano-mechanical properties of Annulus Fibrosus using Atomic Force Microscopy. Micron 39:1008-1019.
12. Yourek G., Hussain M.A. and Mao J.J. (2007): Cytoskeletal Changes in Mesenchymal Stem Cells During Differentiation. ASAIO Journal 53: 219-228.
13. Xin X., Hussain M.A. and Mao J.J. (2007): Continuing differentiation of human mesenchymal stem cells and induced chondrogenic and osteogenic lineages in electrospun PLGA nanofiber scaffold. Biomaterials 28(2): 316-325. Epub 2007, Sep 27.
14. Clark P.A., Clark A.M., Rodriguez A., Hussain M.A. and Mao J.J. (2007): Nanoscale characterization of bone-implant interface and biomechanical modulation of bone ingrowth. Materials Science and Engineering C 27: 382-393.
15. Clark P.A., Rodriguez A., Sumner D.R., Hussain M.A. and Mao J.J. (2005): Modulation of bone ingrowth of rabbit femur titanium implants by in vivo axial micromechanical loading. Journal of Applied Physiology. May; 98(5): 1922-9. Epub 2005 Jan 7.
16. Hussain M.A., Agnihotri A. and Siedlecki CA (2005): AFM imaging of ligand binding to platelet Integrin aIIbB3 Receptors Reconstituted into Planar Lipid Bilayers. Langmuir 21(15): 6979-6986.
17. Hussain M.A., Siedlecki CA (2004): The platelet integrin alpha(IIb) beta(3) imaged by atomic force microscopy on model surfaces. Micron 35(7): 565-573.
18. Hussain M.A., Merchant S.N., Mumbasawala L. and Puniyani R.R. (2004): A decrease in effective diameter of rat mesenteric venules due to leukocyte margination induced by pentoxifylline – A videomicroscopic observation. Microvascular Research 67(3): 237-244.
19. Hussain, M.A., Puniyani, R.R.(1999): Relationship between Power Law Coefficients and Major Blood Constituents Affecting the Whole Blood Viscosity, Journal of Biosciences 24(3): 329-337.
20. Hussain, M.A., Murali, C.V., Willi, P., Bhuvneshwar, G.S. and Sharma, C.P. (1998): Comparative complement activation study of polypropylene hollow fibers of two different make under static condition. Journal of Biomaterials Applications 12: 300-320.
21. Hussain, M.A., Puniyani, R.R. and Kar, S. (1996): Blood perfusion studies in cerebrovascular accidents, hypertensives, diabetics and healthy controls. Clinical Hemorheology 16(2): 165-176.
22. Hussain, M.A., Puniyani, R.R. and Kar, S. (1995): Blood viscosity autoregulation factor in cerebrovascular accidents and high risk cases - A new approach. Clinical Hemorheology 15(1): 61-71.
23. Khan, M.M., Puniyani, R.R., Huilgol, N.G., Hussain, M.A. and Ranade, G.G. (1995): Hemorheological profiles in cancer patients. Clinical Hemorheology 15(1): 37-44.
24. Hussain, M.A., Puniyani, R.R. and Kar, S. (1994): Quantification of blood viscosity using power law model in cerebrovascular accidents and high-risk controls. Clinical Hemorheology 14(5): 685-696.
25. Hussain, M.A., Puniyani, R.R. (1997): Microcirculation and Image Engineering: Promises of Laser Doppler Flowmetry - From Monitoring to Imaging. JAPI 45(12): 967-971.
26. Hussain, M.A., Puniyani, R.R. (1995): Hemorheology in cerebrovascular accidents - An overview. JAPI 43(4): 283-286.

1. Bahattin Karagözo?lu, Nazeeh Shuja Al-Othmany, Mohammed Asif Hussain, Abdelhameed Fouad Al-Khateeb (2012). A New Master of Science (M.Sc.) Program in Biomedical Engineering (BME) at King Abdulaziz University (in preparation).

1. Mohammad A. Hussain, Nazeeh S. Al-othmani, and Rabah W. Aldhaheri (2013): Nanoimaging: A Nanotechnology Perspective of Receptor-Ligand Interaction. In: Nanotechnology, vol. 12: Bioimaging, Shishir Sinha and Naveen Kumar Navani (Eds.), J.N. Govil (Ex. Ed.), Stadium Press LLC (P.O. Box 722200, Houston, TX 77072 - U.S.A.). pp. 27-44. ISBN : 1-62699-012-3; SERIES ISBN : 1-62699-000-X
2. Khlaid, P., Hussain, M.A., Rekha P.D., Suman V.B. and Arun A.B. (2012): Modification of carbon nanotubes for bio-applications and toxicity evaluation. In: Nano Biomaterials, Rajendran V., Prabu P. and Geckeler K.E. (Eds.), Bloomsbury Publishing, India Pvt. Ltd., (London, New Delhi, New York, Sydney), pp. 155-160.
3. Hussain, M.A. and Niimi H. (1998): Hemorheology and Brain Microcirculation. In: Applied Clinical Hemorheology, Puniyani R.R. and Niimi H. (Eds), Quest Publications, Mumbai, India, pp. 62-93.

1. Abdelmoamen K. Aljehani, Mohammed A. Hussaini, Mohammad A. Hussain, Nazeeh Sh Alothmany, and Rabah W. Aldhaheri (2014). Effect of Electrospinning Parameters on Nanofiber Diameter Made of Poly (vinyl alcohol) as Determined by Atomic Force Microscopy. Accepted for presentation in 2nd Middle East Conference on Biomedical Engineering, to be held Hilton Hotel, Doha, Qatar, (IEEE listed conference) February 17-20, 2014. ISBN : 1-62699-012-3; SERIES ISBN : 1-62699-000-X
2. Rama Adari, Debashree Banerjeey, Swaroop Ganguly, Rabah W. Aldhaheri, Mohammad A. Hussain, and Dipankar Saha (2012). Characteristics of Ferromagnetic Schottky Diodes on Heavily n-Doped GaN Semiconductor, to be presented in The 8th EDSSC, sponsored by Electrical Engineering Department, Chulalongkorn University, Bangkok, IEEE Thailand Section, IEEE Electron Device Society, and IEEE ED/SSC Hong Kong Joint Chapter, Bangkok, Thailand during December 3-5. 
3. Paper presented in ISI listed conference AMEE (2012). Submission ID is IWNO-47 and titled is "Cl₂/Ar Based Dry Etching of GaCrN using Inductively Coupled Plasma" (ISI listed conference) http://iwno.iwamee.com/JNO.html
4. Bahattin Karagözo?lu, Nazeeh S. Al-Othmany, M. A. Hussain, and Abdelhameed F. Al-Khateeb (2011). A Proposal for Master of Science (M.Sc.) Program in Biomedical Engineering (BME) at King Abdulaziz University. In: Proceeding of the first Middle East Conference on Biomedical Engineering (MECBME’11), Sharjah, UAE, Feb. 22-25.
5. Hussain, M.A. (2006): Nanotechnology for Implants, Devices and Stem Cell Based Tissue Engineering. In: Proceedings of All India Seminar on Vistas of Nano Applications. 6-7 January 2006, IE(I)-KSC, Bangalore, India. pp. 99-103.
6. Hussain, M.A., Nakajima, T. and Niimi, H. (1996): The time-change of cell-free layer in cat cerebral microvessels in halothane induced hypotension: Dependence of layer thickness on flow shear rate. In: Microcirculation annual (1996), Japanese Society for Microcirculation. Eds. Tsuchiya, M., Asano, M. and Tsushima, N. (Nihon-Igakukan, tokyo, Japan), 12, pp. 109-110.
7. Hussain, M.A. (1995): In-vivo measurement and analysis of cerebral microvascular flow distribution and regulation using a multiple-fiber laser Doppler and an Intravital videomicroscopy. In: Annual Report of Sasakawa Health Science Foundation, (3), pp. 69-71.
8. Hussain, M.A. and Puniyani, R.R. (1994): Microcirculation and hemorheology in cerebrovascular accidents and hypertension: An application of laser Doppler flowmetry. In: Proceedings of 16th Annual Intíl Conference of the IEEE Engineering in Medicine and Biology Society (EMBS), Engineering Advances: New opportunities for Biomedical Engineer 1994. 1, pp. 39-40.
9. Puniyani, R.R., Khan, M.M. and Hussain, M.A. (1994): Radiation effects in malignancy: a study using laser Doppler flowmetry In: Proceedings of 16th Annual Intíl Conference of the IEEE Engineering in Medicine and Biology Society (EMBS), Engineering Advances: New opportunities for Biomedical Engineer 1994. 2, pp. 956-957.

1. Rama Adari, Debashree Banerjeey, Swaroop Ganguly, Rabah W. Aldhaheri, Mohammad A. Hussain, and Dipankar Saha (2012). Characteristics of Ferromagnetic Schottky Diodes on Heavily n-Doped GaN Semiconductor, presented in The 8th EDSSC, sponsored by Electrical Engineering Department, Chulalongkorn University, Bangkok, IEEE Thailand Section, IEEE Electron Device Society, and IEEE ED/SSC Hong Kong Joint Chapter, Bangkok, Thailand during December 3-5.
2. Hussain M.A., Yourek G. and Mao J.J. (2006): Nanomechanobiology of Cytoskeletal Changes in Mesenchymal Stem Cells. Presented at ASAIO's 52nd Annual Conference held in Chicago, IL, USA, June. 
3. Hussain, M.A., Yourek, G. and Mao J.J. (2006): Nano-Mechanobiology of Drug-Induced Cytoskeletal Structure Changes In Mesenchymal Stem Cells Before and After Differentiation Into Bone and Cartilage Forming Cells. Presented in the XVI Conference of Society for Biomaterials and Artificial Organs – India, on Biomaterials, Tissue Engineering and Medical Diagnostics, IIT Delhi, February 24-26.
4. Xin X., Moioli E.K., Hussain M.A. and Mao J.J. (2005): Characteristics and proliferation of human mesenchymal stem cells seeded in electrospun PLGA nanofibers. Presented in the Society for Biomaterials 30th Annual Meeting, Memphis, Tennessee, USA, April 27-30.
5. Hussain M.A. and Siedlecki C.A. (2004): Functional AFM imaging of ligands binding to platelet integrin ?IIb?3 receptors reconstituted into planar lipid bilayer. Platform presentation made at 48th Annual Meeting of Biophysical Society, Baltimore, MD, February 14-18. Original Abstract Control Number: 04-A-1472-BPS
6. Hussain M.A. and Siedlecki C.A. (2003): Atomic Force Microscope Imaging of Nanogold Labeled RGD Peptides Bound to Platelet Integrin alphaIIbetaIII. Presented in the Society for Biomaterials 29th Annual Meeting, Reno, Nevada, USA, April 30- May 3.
7. Hussain M.A. and Siedlecki C.A. (2002) “Atomic Force Microscopy of Platelet Integrin alphaII betaIIIa Adsorbed on Model Surfaces. Presented in the Society for Biomaterials 28th Annual Meeting, Tampa, Florida April 24-28.
8. Hussain M.A. and Siedlecki C.A. (2002): The structure of the platelet integrin ?IIb?IIIa on model surfaces imaged by Atomic Force Microscopy (abstract): Platform presentation made at 46th Annual Meeting of Biophysical Society, San Francisco, CA, February 23-27.